Biomedical Imaging Systems II: Targeted Molecular Imaging in Disease

Topics

• To expose students interested in biomedical research or clinical practice to fundamentals of modern imaging methods and interpretation Establish a foundational understanding of MRI (multi-spectral), PET/SPECT, Ultrasound (including photo-acoustic imaging), and emerging methods including MPI Discuss the design of targeted molecular contrast agents for each modality across myriad biological applications Discuss limitations to each targeted approach including non-specific binding, unbound probe clearance, signal decay, etc. To learn quantitative approaches to analyze biomedical images (includes pharmacokinetic models, attenuation correction, cross modality registration, etc.) To discuss imaging ethics in the context of data interpretation Reinforce mathematical principles relevant to image analysis including linear algebra, convolution and differential equations Establish proficiency in the use of MATLAB as a tool for analyzing biomedical imaging data
• Understand the devices, techniques and protocols used for in vivo imaging in research and clinical settings Analyze imaging data derived from imaging studies using commonly utilized image processing techniques Critically evaluate scientific publications in the molecular imaging space.

Official catalogue course objectives and student learning outcomes