Epidemiologic Methods II
This course is an intermediate level course in epidemiology. It replaces previously approved and delivered courses PHW250F and PHW250G. Topics include causal inference; measurement of disease rates; inferential reasoning; research study designs, ecologic, case-control, cohort, intervention trials, meta-analytic designs; potential sources of bias, confounding, effect modification in research design are explored in depth; topics in clinical epidemiology, likelihood ratios, receiver operator curves, the sensitivity, specificity, predictive value of a test; brief introduction to logistic regression and survival analysis. Topics are covered at a advanced level than PH250A or PHW250. Readings from this course provide a firm foundation for PH250C.
Topics
- • Apply causal frameworks to the assessment of causality in associations • Calculate and interpret measures of disease and association. • Identify appropriate applications of measures of disease and association. • Define the major study designs, including their strengths and weaknesses, and demonstrate their appropriate applications • Explain sources of bias in studies • Identify design and analysis approaches to reduce bias in studies • Assess the extent of bias in studies and calculate bias-corrected measures • Define, calculate and interpret effect measure modification on different scales • Explain the purposes, mechanics and limitations of matching in study designs • Identify and apply appropriate analytic techniques for study questions, and interpret coefficients and other quantities estimated using these techniques. • Define, calculate and interpret power, sample size, confidence intervals and p-values. • State the purposes of screening, and calculate and interpret screening measures. Explain the purposes and process of systematic review and meta-analysis.
Official catalogue course objectives and student learning outcomes
Prerequisites & course information
{'preRequisiteCourse': '1178901', 'concurrentPrerequisit': False}; {'preRequisiteCourse': '1176901', 'concurrentPrerequisit': False}; {'preRequisiteCourse': '1175091', 'concurrentPrerequisit': False}; {'preRequisiteCourse': '1178902', 'concurrentPrerequisit': False}
Sources
- Course catalogue ↗2026-2027