Blood Substitutes: Principles and Therapeutics Development

Blood serves many critical functions including respiratory gas transport, hemostasis and host defense. Plasma and cellular components of blood, their functional mechanisms, pathophysiologic consequencies when deficient and current treatments will be reviewed. Finally, development of blood component substitutive therapeutics (blood substitutes) based on protein and cellular engineering technologies (biotherapeutics) will be discussed. Open to Graduates students and Juniors and Seniors who meet the pre-requisites BIOL 0800 and BIOL 0280 or with instructor's permission.