Mechanisms of Protein Synthesis and Impact on Human Disease

This course will examine mechanisms central to the regulation of protein synthesis in both prokaryotes and eukaryotes. Targeting protein synthesis through ribosomes is a proven drug target commonly used to treat many infectious diseases. The regulation of protein synthesis in eukaryotes is critical for myriad human conditions including aging and cancer, including the recently discovered role of microRNAs. This course will explore the common and unique mechanisms of regulation of protein synthesis between prokaryotes and eukaryotes and the importance of understanding these mechanisms for human health. For graduate students and advanced undergraduates with permission.