The Immune System

Introduction to the experimental and theoretical foundations of immunology and the function of the mammalian immune system. Focuses on concepts, landmark experiments and recent advances. Topics include innate and adaptive immunity; structure/function of antibody molecules and T cell receptors; and regulation of immune responses through cellular interactions. Application of concepts to medically significant issues (vaccines, transplantation, hypersensitivity, autoimmunity, cancer, immunodeficiency) is discussed. Interpretative analysis of experimental data is emphasized. Activities include written assignments that analyze a hypothetical immune system and a final paper addressing an immunological topic of the student's choosing. For Pfizer students only.