Proteins and Proteomics

3 credits · Undergraduate Programs

Protein structure and chemistry: structural motifs, ligand-binding, conformational changes, chemical modification; protein folding; structure prediction by molecular modelling. Identification of proteins in the proteome: 2D gel electrophoresis and chromatography, mass spectrometry; metalloproteins; post-translational modifications; protein-protein interactions. Prerequisite(s): Biology 331; Biochemistry 341 or 393; and Chemistry 353 or 355. Antirequisite(s): Credit for Biochemistry 431 and 531 will not be allowed.