Epigentics & Chromatin Dynamics

1 credits · Graduate Programs

Fundamentals of eukaryotic chromatin assembly, dynamic chromatin regulation and post-translational modifications that comprise epigenetics. DNA methylation, histone post-translational modifications, histone variants, regulatory siRNA, nucleosome remodelling and higher-order chromatin organization. Cancer and disease-associated epigenetic alterations will be discussed in detail. Prerequisite(s): Consent of course co-ordinator. Preference will be given to those in the Biochemistry and Molecular Biology graduate program or the Cancer Biology Specialization of the Medical Science graduate program.