Macromolecular Function: kinetics, energetics, and mechanisms

9 units (3-0-6) | first term

Discussion of the energetic principles and molecular mechanisms that underlie enzyme's catalytic proficiency and exquisite specificity. Principles of selectivity, allostery, and force generation in biology. Practical kinetics and their application to more complex biological systems, including steady-state and pre-steady-state kinetics, and kinetic simulations.