The Neurobiology of Homeostasis

3 Units

This course will explore the relationship between the body and the brain through homeostasis from its development to its decline, while reviewing the known literature and discussing unanswered questions. Students will learn the basics of homeostasis in normal nervous system development and consider current research investigating perturbations leading to disorders and abnormal development. Systems that interact with the central nervous system, including the endocrine system, the immune system, and the enteric system, will be introduced and impairments in nervous system communication with these systems will be discussed in regards to neurological diseases, neuropsychiatric disorders, and injury and repair, while incorporating discussions of current diagnostic techniques, prevention and treatment. The conclusion of the course will focus on changes in the nervous system that lead to cognitive decline, memory impairments and motor deficits common in aging and neurodegenerative disorders. The overarching theme will focus on homeostatic mechanisms and how their impairment can have detrimental effects on the nervous system and its interactions with the peripheral systems throughout the lifespan. Prereq: NEUR 201 .