Entrepreneurship and protein-based drug development

6 units · Graduate

Spring: 6 units This is a course for students with background in biochemistry who want to learn about business opportunities and advances in protein-based treatments. As protein-based biologic drugs become more and more prevalent understanding the role of protein-protein interactions is vital for both design and production of biologic drugs. We will focus on the fundamentals of protein-interactions, giving examples of protein-protein interactions in important cellular pathways. We will also focus on how protein-protein interactions are used in the processing of biologic drugs, were antibody-Protein A interactions are key for the purification of antibody-based biologics. We will study case-studies of how the pharmaceutical industry develops biologics from conception, through FDA approval, to mass production. Prerequisites: 03-709 or 03-231