Analytical Techniques for Bioprocessing

6 units · Graduate

Spring: 6 units This laboratory course will introduce students to analytical techniques used in the characterization of the products of biomanufacturing processes, including monoclonal antibodies, mRNA vaccines, and viral vaccines. Students will use spectroscopic methods (UV-vis, Raman, circular dichroism, and fluorescence), chromatography (HILIC, SEC, HPLC, and UPLC), as well as light scattering and electrokinetic methods. Lab teams will investigate materials used in vaccine products and therapeutics in weekly, team-based labs. Weekly lab reports are completed with a significant research component using resources from the literature. This course assumes prior knowledge of material covered in 03-776 Molecular Techniques for Bioprocessing and 06-685 Bioseparations and Bioprocess Analytical Technologies. Prerequisite: 03-776 Min. grade C