Cancer Biology and Metabolism

3.0 credits · Graduate

Cancer is a global health problem often associated with high mortality due to therapeutic resistance. Metastasis, uncontrolled growth, metabolic reprogramming and oncogenic alterations are major features of most cancers and contribute to poor survival outcome in patients. Late diagnosis, cancer disparity and limited understanding of how cancers arise are also problems. We are in a modern era of multi-omics technologies including genomics, proteomics, epigenetics, and metabolomics, which are enabling unprecedented insights into the biology of cancer. This course will provide an overview on the fundamentals of cancer biology such as cancer hallmarks, signal transduction, genetics/gene mutations, therapeutic concepts such as synthetic lethality, cancer models, research methods and data analytical tools. Further, the course will introduce metabolism and metabolomics techniques.