Regulation of Macronutrient Metabolism

Topics

• Demonstrate an integrative understanding of macronutrient metabolism and how it is regulated in humans.
• Describe roles of macronutrients in providing fuels and synthetic substrates for net tissue deposition.
• Synthesize factual knowledge into an understanding of how macronutrient metabolism changes in response to food intake versus food deprivation and the major ways in which this is regulated in key tissues.
• Synthesize factual knowledge into a conceptual framework for the functions of macronutrient metabolism and its regulation in normal physiological processes (developmental programming, growth, immune function, regulation of food intake and energy expenditure, etc.
• Synthesize factual knowledge into a conceptual framework for understanding how macronutrient metabolism and its regulation (dysregulation), including tissue-specific roles, may contribute to disease or poorer health outcomes (e.g., obesity, metabolic disease, premature aging, malnutrition, impaired immune function).
• Describe functions of essential macronutrients (e.g., n-3 and n-6 fatty acids, essential amino acids).
• Describe metabolism of lipoprotein and cholesterol metabolism including their normal roles in macronutrient metabolism and disease processes.
• Use DRIs for macronutrients and energy and food composition data to calculate desirable energy and macronutrient intakes.

Official roster learning outcomes