Enzymes

3 credits · Graduate

Fundamental principles of enzyme catalysis and its regulation are examined. Topics include enzyme kinetics, enzyme inhibition and inactivation, isotope effect measurements, site-directed mutagenesis, and the active site architecture and transition state stabilization of selected enzymes. Classic and current papers in the literature are reviewed and the experimental and conceptual approaches are critically appraised. EXCLUSIONS: BIOC 4701 FORMATS: Lecture | Seminar