Foundational Biomaterials Science

3 credits · Professional

This course provides an introduction to the synthesis, processing, and application of materials science for use in clinical dentistry and other biomedical applications. The materials science of metals, polymers, ceramics and glasses, and composite materials is introduced, including structure-property relations, mechanical behavior, and the roles of driving force and mechanism in materials changes. This introduction is followed by consideration of the biological performance of materials (material and host responses) as they form the basis for understanding of the concept of biocompatibility for implanted materials and devices. Under the material response, corrosion of metals, swelling and leaching of materials and biodegradation of polymers have special focus. Under the host response, the modulation by implanted materials of host biology is considered, with emphasis on inflammation and wound healing, specific and non- specific immunity, coagulation, and infection. This course provides students with the opportunity to develop critical thinking appropriate to the application of biomaterials science in dentistry, with development of skills for interpretation and application of the biomedical literature.