Computational Genomics and Epigenomics

3 Credits

Genomics and epigenomics utilize high-throughput sequencing technologies in understanding biology questions. The primary goal of this course is to introduce history, theory, latest advances, and computational approaches in (epi)genomics for conducting large-scale genomic analyses. Course topics include sequence alignment, genome assembly and annotation, variant identification, transcriptomics, small RNAs, DNA methylation, histone modification, open chromatin region, and 3D chromatin interaction.