Structural Biology

3 Credits · Level: Graduate, Undergraduate

The aim of this course is to integrate the chemical and physical sciences to provide the molecular basis of protein function using structural biology approaches as tools. For an understanding of biological function, a detailed knowledge of the three-dimensional structures of biological macro-molecules and their interactions with ligands is required. This course will provide the basic knowledge needed to understand “structure-function” relationships and concepts of drug design. Students will understand the effect of mutations in disrupting the three-dimensional structure and ultimately leading to diseases. Students will also be exposed to basic concepts of pharmacogenomics. The course is suitable for scientists wishing to update their knowledge of molecular structural biology, or as part of the background studies of research students, particularly those whose undergraduate studies were in a different area.