Stat. Genetics Genomics

3 Credits · Level: Graduate

This is a course for both master and Ph.D students in epidemiology, statistics, medical genetics and molecular biology. It introduces probabilistic and statistical methods in analyzing genetic data arising from human and animal studies, gene mapping, molecular genetics, and DNA sequencing. Topics include basic concepts in human genetics, sampling design in human genetics, gene frequency estimation, Hardy-Weinberg equilibrium, linkage disequilibrium, association and transmission disequilibrium test studies, linkage and pedigree analysis, classical segregation analysis and ascertainment, polygenic models, complex segregation analysis, and DNA sequence data analysis.