ExpMethods in Biophysical Chem

3 Credits · Level: Graduate, Undergraduate

The goal of this course is to provide rigorous, quantitative theory and hands-on laboratory experience on the physical principles governing the structure-function relationship of biological macromolecules. The course has three modules. The first two modules are experimental, and are focused on two distinct but complementary sets of biophysical experiments that integrate calorimetric and spectroscopic approaches to study protein stability, folding and ligand binding. The third module involves computational modeling, statistical analysis of data using non-linear curve fitting models, and error analysis.