Physiological Adaptations

0-4 Credits · Level: Graduate, Undergraduate

One of the striking capacities of humans is our ability to adapt to different environments. In this course, we explore this capacity for adaptation to specific conditions of stress, ie, an alteration in a physiological variable determined to be a threat to the organism, with an emphasis on the timeline of such responses. Specific modules and topics highlight mechanisms of adaptation at the systems and cellular levels and will be facilitated primarily through individual student presentations. Additionally, students will hone their skills in scientific argumentation through an iterative writing process in response to several prompts. Finally, students will collaborate in small groups to explore and clarify responses to multiple, simultaneous stresses. The primary resource for this course will be the biomedical literature, accessed through databases such as MEDLINE. OBJECTIVES: (1) To appreciate the immense adaptability of the human body for habitation in environments with extremes in gravitational, altitudinal, behavioral, and other stimuli. Independent and group-based review of the scientific literature will facilitate such an appreciation. In particular, we will analyze and evaluate the data from the primary literature to support arguments for human adaptation to extreme conditions. (2) To navigate effectively the challenges of collecting physiological data in extreme environments and in obtaining relevant information from terrestrial simulations of extreme environments. In our review of the literature, we will analyze and evaluate the methods and experimental design associated with studies to support arguments for human adaptation to extreme conditions. (3) To transition from traditional didactic learning modes to a self-led exploration of information and data that is specific to each student. You will be challenged to find answers to your scientific questions and, more importantly, determine your position on an issue that is ambiguous in the scientific literature. Additionally, as noted above, you will transition to and gain comfort with scientific knowledge as arguments supported by scientific data. (4) To learn of the benefits to human health and health practice through understanding the results of human adaptation to extreme environments. Theoretical application of such concepts will be demonstrated in a semester-long group project in which you will provide support for physiological phenomena that have yet to be fully understood or explained. The lecture portion of this course will be co-taught by the instructors listed. This is a linked section. Registration in another linked section of this course is required.