Clinical Metabolomics

2 Credits · Level: Graduate, Undergraduate

This didactic course is designed to provide students an in depth understanding of molecular phenotyping technologies for basic, clinical and translational research. The course will cover the basics of mass spectromtery based metabolomics approach. We will discuss strategies for data generation as well as multivariate data mining tools and finally the clinical applications of this technology for studying disease onset and progression, drug metabolism and toxicity, discovery and validation of disease biomarkers and the effect of different treatments (drugs, radiation etc.) on the overall metabolism. The course will also include laboratory sessions that would provide practical insights into operations of a mass spectrometer and the use of interactive software for data analysis.