Principles of Genetic Epidemiology

Harvard HSPH

Introduces the basic principles and methods of genetic epidemiology. After a brief review of the history of genetic epidemiology and fundamentals of genetics, methods for analysis of common and rare and rare alleles, especially as derived from high throughput genomic data, will be discussed. Methods related to genome-wide association studies (GWAS) are a particular focus and cover downstream uses of GWAS results in polygenic risk scores and Mendelian randomization. The contribution of genetic…