Physical Biochemistry: Understanding Macromolecular Machines

Harvard FAS

This course develops your understanding of fundamental biochemistry concepts and how they are applied in cutting-edge structural and molecular biology research. You will learn about protein and nucleic acid structure, thermodynamics, kinetics, and intermolecular interactions while exploring techniques like cryo-electron microscopy, AlphaFold protein structure prediction, molecular dynamics, and protein design with Rosetta. The course emphasizes applying these concepts to cell signaling,…