Exploring Biomolecular Properties and Interactions by NMR Spectroscopy

3 Credits.

NMR is a powerful spectroscopic technique which exploits the magnetic properties of atomic nuclei to provide unique, atomistic level resolution and insights into molecular properties such as structure, dynamics and structure-function relationships, both in solution and solid state. In this course, we will learn about the basics of solution state NMR spectroscopy, acquire 1D and 2D NMR spectra and use various NMR experiments to characterize and probe properties of biomolecular systems ranging from small metabolites to large proteins and nucleic acids as well as functionally relevant interactions, at atomic level resolution. The format will include lectures and hands-on data collection sessions in the JHU Biomolecular NMR Center.