Genome Integrity

3 Credits.

Provides students with a broad base in fundamental principles of genome integrity. Examines connections between genome integrity, organism fitness, and human diseases and disorders. Addresses 1) Homologous recombination, (2) Non-homologous end joining, (3) Mismatch repair, (4) Transposable elements, (5) Topoisomerases, (6) Structural maintenance of chromosomes and (7) Chromosome segregation.