PH.140.609
Improving Precision and Power in Randomized Trials by Leveraging Baseline Variables
Explains what covariate adjustment is, how it works, when it may be useful to apply, and how to implement it (in a preplanned way that is robust to model misspecification) for a variety of scenarios. Demonstrates the impact of covariate adjustment using trial data sets in multiple disease areas. Provides step-by-step, clear documentation of how to apply the software in each setting. Applies the software tools on the different datasets in small groups.
Sources
- Course catalogue โ2026โ2027