Advanced Methods for Design and Analysis of Cohort Studies

5 Credits.

Explores advanced methods useful for the design and analysis of cohort studies. Emphasizes methods for analyzing time-to-event data subject to staggered entries using advanced parametric and semi-parametric methods; analytical methods for incomplete observations in cohort studies; methods to measure effects of exposures on time-to-event using relative times and relative hazards; parametric survival analysis methods and taxonomy of hazard functions; coefficients of determination based on parametric models for survival data; regression methods for trajectories of biomarkers; methods for the analysis of interventions in observational studies: confounding by indication, marginal structural models for individual effectiveness; methods for estimating population effectiveness; and methods to jointly analyze longitudinal and survival data.