(BIOE 307) Structural Bioinformatics

3 Credits

Computational techniques and principles of structural biology used to examine molecular structure, function, and evolution. Topics include: protein structure alignment and prediction; molecular surface analysis; statistical modeling; QSAR; computational drug design; influences on binding specificity; protein-ligand, -protein, and -DNA interactions; molecular simulation, electrostatics. Tutorials on UNIX systems and research software support an interdisciplinary collaborative project in computational structural biology. Credit will not be given for both CSE 307 and CSE 407 . Must have junior standing or higher. Prerequisites: BIOS 120 or CSE 109 or CHM 113 or MATH 231 Attribute/Distribution: Q