Epigenetics in Development and Human Diseases

1.5 cr · Graduate

Emphasis on current understanding about the dynamic mechanisms that instruct when and where genomic DNA is turned on or off. We will discuss the epigenetic mechanisms that control differentiation of specialized cell types during development. Additionally, this course will highlight recent advancements on the impact of epigenetics in neurodevelopmental diseases with regards to the etiology, progression, diagnosis and treatment. In this respect, application of stem cell biologyin regenerative medicine, genome-wide genetic-epigentic strategies and gene therapy approaches will be discussed.