Metabolic Pathway Engineering

3 Credits

The state-of-the-art in metabolic engineering, with a focus on the analysis and engineering of metabolic pathways through (chemical) engineering principles, will be covered. Topics covered include: (1) overview of biochemistry and metabolism; (2) metabolic flux analysis and isotope labeling illustrated with examples from the recent scientific literature; (3) technologies for engineering metabolic pathways; (4) metabolic control analysis and pathway regulation; (5) applications of metabolic engineering to synthesis of biofuels and therapeutics; (6) specialized and related subjects such as protein engineering and synthetic biology.