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BIOCHEM 3Z03

STRUCTURAL DETERMINATION AND ANALYSIS OF MACROMOLECULES

Undergraduate

Winter 2026

Topics

  • X-ray crystallography
  • Cryo-electron microscopy
  • AI structure prediction
  • Small-angle X-ray scattering
  • NMR
  • Atomic force microscopy
  • Protein-structure interpretation

Readings

  • Crystallography Made Crystal Clear: A Guide for Users of Macromolecular Models
    Gale Rhodes · optional
  • Biomolecular Crystallography: Principles, Practice, and Application to Structural Biology
    Bernhard Rupp · optional
  • Introduction to Macromolecular Crystallography
    Alexander McPherson · optional
  • Advances in Protein Molecular and Structural Biology Methods
    optional
  • Optional online resources on crystallography, iMosflm, PyMOL, Phenix, SAXS and cryo-EM are listed on the final page.
    See source
Sources