BIOTECH 3BP3
Bioreactor Processes and Design
Fall 2026 · C01
Topics
- Introduction to chemical reactor design Reaction rates and reactor types
- Reaction rates and reactor sizing
- Reactors in series
- Enzymes: Principles, kinetics (Rapid equilibrium & quasi state-state), Michaelis-Menten Manipulation of experimental data
- Enzymes: Inhibited Enzyme Kinetics, complex enzyme kinetics
- Enzymes: Immobilized Enzymes
- Mass-Transfer Limitations for Immobilized Enzyme
- Continuous cell growth: Growth cycle, yield coefficients
- Continuous cell growth: Effect of temperature, pH, oxygen, inhibition
- Continuous cell growth: The ideal Chemostat
- Bioreactor considerations: Chemostat with recycle, multistage Chemostat, fed-batch operation, perfusion systems
- Bioreactor selection and scale-up
Readings
- Bioprocess EngineeringISBN 0137062702
- Biochemical Engineering
- Elements of Chemical Reaction Engineering
- Chemical Reaction Engineering
- Bioprocess Engineering ISBN: 0137062702 Authors: Michael Shuler et al
Fall 2025 · Bioreactor Processes & Design · C01
Readings
- Etext Bioprocess Engineering: Basic Concepts - 6 Month AccessISBN 9780137459469
Fall 2023
Topics
- Overview of fermentation technology and bioprocessing
- Kinetics and thermodynamics of microbial processes
- Mass transfer in immobilized systems
- Analysis of batch and continuous processes
- Bioreactor design and analysis
- Operation and control
- Instrumentation
- Oxygen transfer
- Scale up
Readings
- Bioprocess Engineering, 3rd Edition, 2017; Michael Shuler et al.; ISBN 0137062702ISBN 0137062702