MOLECULAR GENETICS OF EUKARYOTES

Topics

• Unit 1 – Introduction: Characterization of the Eukaryotic Genome
• No tutorial
• Unit 2 – Control of Gene Expression: Review of Basic Principles
• Introductory tutorial – TA will provide information on format of tutorials & selection of topics
• Unit 3 – Active and Repressed Chromatin: An Overview (Guest lecture with Stephanie Al Fairbairn)
• Unit 4 – Histone Code
• Tutorial 1 – Transposable elements & genome defence
• Unit 5 – Control of Gene Expression at the Chromatin Level
• Tutorial 2 – Repetitive DNA, enhancers & nuclear architecture
• Unit 6 – Role of Non-coding RNAs in Chromatin Modification & Gene Expression Thursday, February 12, 2026 – Midterm (will be held during regular class time, room TBD)
• No tutorial (week of midterm)
• Unit 7 – Pioneering Transcription Factors in Gene Activation