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MOLBIOL 4K03

RESEARCH ADVANCES IN BIOLOGY OF AGING

Undergraduate

Fall 2025 · T01

Topics

  • Overview on hallmarks of aging.
  • Telomeres, telomerase and telomere attrition
  • DNA repair and genomic instability
  • Histone modification, DNA methylation and epigenetic alterations
  • Cellular senescence
  • Deregulated nutrient sensing and mitochondria dysfunction
  • Loss of proteostasis
  • Altered intercellular communication and stem cells exhaustion
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