Methods of Biophysical Chemistry

3 credits · Undergraduate credit

This course provides an overview of key methodologies of contemporary biophysics and biophysical chemistry. Principles of structure determination by X-ray diffraction, solution and solid-state NMR and electron microscopy will be covered. A variety of optical spectroscopic techniques, including UV/Vis, fluorescence, circular dichroism and cell imaging will be discussed. Methods for the separation and study of biological macromolecules and membranes including utracentrifugation, chromatography, electrophoresis, mass spectometry and calorimetry will be introduced.