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12.178

The Phylogenomic Planetary Record

3-0-9 units · Undergraduate

Introduces the tools of sequence-based phylogenetic analysis and molecular evolution in the context of studying events in Earth's deep past that have been preserved by genomes. Topics include basic concepts of cladistics, phylogeny and sequence evolution, construction of phylogenetic trees of genes and microbial lineages, molecular clocks, dating, and ancestral sequence reconstruction. Special attention to the evolutionary history of microbial metabolisms and their relationship to global biogeochemical cycles across Earth's history. Students taking graduate version complete additional assignments.

Prerequisites & course information

Subject meets with 12.478 Prereq: None Acad Year 2027-2028: Not offered Acad Year 2028-2029: U (Fall) 3-0-9 units

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