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20.483

Noninvasive Imaging in Biology and Medicine

Graduate · Historical course

Fall 2005

Topics

  • Overview of Imaging
  • Interactions of Radiation with Matter
  • X-ray Generation and Planar Imaging
  • X-ray CT Overview
  • Fourier Transforms and Convolution
  • Central Slice Theorem and Projection/Reconstruction
  • Class Demo: X-ray CT
  • Application: Quantitative Anatomy from CT
  • Tracers for Nuclear Imaging
  • Nuclear Imaging Detectors and Cameras
  • Principles of PET and SPECT
  • Application: Binding Measurements with PET
  • Application: Functional Imaging using FDG Uptake
  • Nuclear Magnetic Resonance Physics I
  • Nuclear Magnetic Resonance Physics II
  • Magnetic Resonance Imaging I
  • Magnetic Resonance Imaging II
  • MRI Contrast Agents
  • Application: BOLD Effect in Functional MRI
  • Application: Neural Fiber Tracking with MRI
  • Class Demo: MRI
  • Diffuse Optical Tomography I
  • Diffuse Optical Tomography II
  • Optical Molecular Imaging
  • Final Presentations

Readings

  • Bushberg, Jerrold T., J. Anthony Seibert, Edwin M. Leidholdt, Jr., and John M. Boone. The Essential Physics of Medical Imaging . 2nd ed. Baltimore, MD: Lippincott Williams & Wilkins, 2001. ISBN: 9780683301182.
    Required
  • Cho, Z. H., Joie P. Jones, and Manbir Singh. Foundations of Medical Imaging . New York, NY: Wiley-Interscience, 1993. ISBN: 9780471545736.
    Listed reading
  • Phelps, Michael E. PET: Molecular Imaging and Its Biological Applications . New York, NY: Springer, 2004. ISBN: 9780387403595.
    Listed reading
  • Imaging Radiation Bushberg. Chapters 1-2.
    Listed reading
  • SES #: 2 · TOPICS: Interactions of Radiation with Matter · READINGS: Bushberg. Chapter 3.
    Reading assignment
  • SES #: 3 · TOPICS: X-ray Generation and Planar Imaging · READINGS: Bushberg. Chapter 5-6.
    Reading assignment
  • SES #: 4 · TOPICS: X-ray CT Overview · READINGS: Bushberg. Chapter 13.
    Reading assignment
  • SES #: 5 · TOPICS: Fourier Transforms and Convolution · READINGS: Cho, et al. Chapter 2.1.
    Reading assignment
  • SES #: 6 · TOPICS: Central Slice Theorem and Projection/Reconstruction · READINGS: Cho, et al. Chapter 3.
    Reading assignment
  • SES #: 8 · TOPICS: Application: Quantitative Anatomy from CT · READINGS: Class handout
    Reading assignment
  • SES #: 9 · TOPICS: Tracers for Nuclear Imaging · READINGS: Bushberg. Chapters 18-19.
    Reading assignment
  • SES #: 10 · TOPICS: Nuclear Imaging Detectors and Cameras · READINGS: Bushberg. Chapters 20-21.
    Reading assignment
  • SES #: 11 · TOPICS: Principles of PET and SPECT · READINGS: Bushberg. Chapters 22.
    Reading assignment
  • SES #: 12 · TOPICS: Application: Binding Measurements with PET · READINGS: Phelps. Chapter 2.
    Reading assignment
  • SES #: 13 · TOPICS: Application: Functional Imaging using FDG Uptake · READINGS: Phelps. Chapter 7.
    Reading assignment
  • SES #: 14 · TOPICS: Nuclear Magnetic Resonance Physics I · READINGS: Bushberg. Chapter 14.
    Reading assignment
  • SES #: 15 · TOPICS: Nuclear Magnetic Resonance Physics II · READINGS: Bushberg. Chapter 14.
    Reading assignment
  • SES #: 16 · TOPICS: Magnetic Resonance Imaging I · READINGS: Bushberg. Chapter 15.
    Reading assignment
  • SES #: 17 · TOPICS: Magnetic Resonance Imaging II · READINGS: Bushberg. Chapter 15.
    Reading assignment
  • SES #: 18 · TOPICS: MRI Contrast Agents · READINGS: Lauffer review
    Reading assignment
  • SES #: 19 · TOPICS: Application: BOLD Effect in Functional MRI · READINGS: Class handout
    Reading assignment
  • SES #: 20 · TOPICS: Application: Neural Fiber Tracking with MRI · READINGS: Class handout
    Reading assignment
  • SES #: 22 · TOPICS: Diffuse Optical Tomography I · READINGS: Class handout
    Reading assignment
  • SES #: 23 · TOPICS: Diffuse Optical Tomography II · READINGS: Class handout
    Reading assignment
  • SES #: 24 · TOPICS: Optical Molecular Imaging · READINGS: Class handout
    Reading assignment
Sources