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3.97

Cell-Matrix Mechanics

Graduate · Historical course

Fall 2014

Topics

  • Clinical Examples of the Roles of Mechanical Forces in Tissues and Organs: The Working Paradigms
  • Unit Cell Processes
  • Tissue Structures and Cell-Matrix Interactions: Integrins
  • Effects of Exogenous Mechanical Forces on Cells/Tissues
  • Effects of Pressure Waves on Tissue: Extracorporeal Shock Waves
  • Support Structures: Molecules and Tissues
  • Thermodynamics of ECM Deformation
  • Student Presentations: Term Report Candidate Topics; Review
  • Student Presentations: Term Report Topic Description
  • Endogenous Mechanical Force Generation by Cells
  • Models for Cell Contraction In Vitro
  • Linear Elastic Models of Tissues
  • Mechanical Coupling of Cells with Matrix
  • Integrin-Ligand Interactions during Regeneration
  • Student Presentations: Term Report Progress
  • Mechanical Behavior of Bone and Response to Loading
  • Poroelastic Models. Cartilage
  • Cardiac Muscle Cell Contraction Guest lecturer: Dr. Yvonne Aratyn-Schaus
  • Viscoelastic Behavior. Skin and Cartilage
  • Viscoelastic Behavior. Skin and Cartilage (cont.)
  • Musculoskeletal Soft Tissue Mechanics; Term Report Due
  • Mechanics of Tendon and Skin; Review

Readings

Sources