5.301
Chemistry Laboratory Techniques
Practical training in basic chemistry laboratory techniques. Intended to provide students with the skills necessary to undertake original research projects in chemistry. Limited to first-year students in IAP (application required); open to all students in spring (enrollment by lottery).
January IAP 2012
Topics
- Introductory Lecture, Pre-Lab Reports and Lab Notebooks
- NMR Spectroscopy
- Extraction Techniques & IR Spectroscopy
- Recrystallization Techniques
- Mass Spectroscopy
- Atmospheric & Vacuum Distillation
- TLC, Column & Gas Chromatography
- Students Present Distillation Results
- Protein Assays - Biochemistry
- Error Analysis
- Original Research Project Charge, Synthesis of Penicillin Derivatives
- Students Present Results of Synthesis and Schemes
- Writing Up The Research Lab Report
- No Lecture
Readings
- Zubrick, James. The Organic Chem Lab Survival Manual: A Student’s Guide to Techniques. 8th ed. Wiley, 2010. ISBN: 9780470494370. (Referred to as Zubrick)
- Leonard, J., B. Lygo, and G. Procter. Advanced Practical Organic Chemistry. 2nd ed. CRC Press, 1994. ISBN: 9780748740710. (Referred to as LLP)
- Mohrig, J. R., C. Noring Hammond, and Paul F. Schatz. Techniques in Organic Chemistry: Miniscale, Standard Taper Microscale, and Williamson Microscale. 3rd ed. W.H. Freeman, 2010. ISBN: 9781429219563.
Prerequisites & course information
Prereq: Chemistry (GIR) and permission of instructor U (IAP) 1-4-1 units
Sources
- Course catalogue ↗2026–2027
- MIT OpenCourseWare ↗January IAP 2012
- MIT OCW calendar ↗
- MIT OCW syllabus ↗
- Historical MIT OpenCourseWare offering. Named reading entries and schedule topics are automatically extracted from the linked source pages.