Biochemistry Laboratory

Spring 2009

The course, which spans two thirds of a semester, provides students with a research-inspired laboratory experience that introduces standard biochemical techniques in the context of investigating a current and exciting research topic, acquired resistance to the cancer drug Gleevec. Techniques include protein expression, purification, and gel analysis, PCR, site-directed mutagenesis, kinase activity assays, and protein structure viewing. This class is part of the new laboratory curriculum in the MIT Department of Chemistry. Undergraduate Research-Inspired Experimental Chemistry Alternatives ({{% resource_link "675c093f-99c1-43f7-a774-61a3efd5de22" "URIECA" %}}) introduces students to cutting edge research topics in a modular format. ##### Acknowledgments Development of this course was funded through an HHMI Professors grant to Professor Catherine L. Drennan.