7.03
Genetics
The principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Structure and function of genes, chromosomes, and genomes. Biological variation resulting from recombination, mutation, and selection. Population genetics. Use of genetic methods to analyze protein function, gene regulation, and inherited disease.
Fall 2004
Topics
- Physical Structure of the Gene
- The Complementation Test and Gene Function
- Mendelian Genetics
- Probability and Pedigrees
- Chromosomes and Sex Linkage
- Recombination and Genetic Maps
- Three-factor Crosses
- Tetrad Analysis
- Phage Genetics
- Gene Structure and DNA Analysis
- Mutations and Suppressors
- Bacterial Genetics: Transposition
- Bacterial Genetics: Transduction
- Complementation in Bacteria: Plasmids
- Complementation in Bacteria: Recombinant DNA
- Prokaryotic Regulation: Negative Control
- Prokaryotic Regulation: Positive Control
- Prokaryotic Regulation: Regulatory Circuits
- Eukaryotic Genes and Genomes I
- Eukaryotic Genes and Genomes II
- Eukaryotic Genes and Genomes III
- Eukaryotic Genes and Genomes IV
- Transgenes and Gene Targeting in Mice I
- Transgenes and Gene Targeting in Mice II
- Population Genetics: Hardy-Weinberg
- Population Genetics: Mutation and Selection
- Population Genetics: Inbreeding
- Human Polymorphisms
- Statistical Evaluation of Linkage I
- Statistical Evaluation of Linkage II
- Complex Traits
- Chromosome Anomalies I
- Chromosome Anomalies II
- Genetics of Cancer I
- Genetics of Cancer II
Readings
- There are no assigned readings for this class although we recommend the following textbook as a valuable reference.
- Griffiths, Anthony J. F., Jeffrey H. Miller, David T. Suzuki, Richard C. Lewontin, and William M. Gelbart. An Introduction to Genetic Analysis . 7th ed. New York: W. H. Freeman, 2000. ISBN: 9780716735205.
Prerequisites & course information
Prereq: Biology (GIR) U (Fall, Spring) 4-0-8 units. REST
Sources
- Course catalogue ↗2026–2027
- MIT OpenCourseWare ↗Fall 2004
- MIT OCW calendar ↗
- MIT OCW syllabus ↗
- Historical MIT OpenCourseWare offering. Named reading entries and schedule topics are automatically extracted from the linked source pages.