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7.05

General Biochemistry

5-0-7 units. REST · Undergraduate

Contributions of biochemistry toward an understanding of the structure and functioning of organisms, tissues, and cells. Chemistry and functions of constituents of cells and tissues and the chemical and physical-chemical basis for the structures of nucleic acids, proteins, and carbohydrates. Basic enzymology and biochemical reaction mechanisms involved in macromolecular synthesis and degradation, signaling, transport, and movement. General metabolism of carbohydrates, fats, and nitrogen-containing materials such as amino acids, proteins, and related compounds.

Spring 2020

Topics

  • Protein Purification I
  • Hemoglobin and Allostery
  • Enzymes as Catalysts
  • Hormones and Signal Transduction I
  • Glycolysis II/Regulation
  • Lipids and Fatty Acid Oxidation
  • Pentose Phosphate Pathway

Readings

  • Readings are from Berg, Tymockzko, Gatto, and Stryer Biochemistry (8th Edition) OR from Miesfeld & McEvoy Biochemistry . Read one or the other. There is no need to read both.
    Listed reading
  • [BTGS] = Berg, Jeremy M., John L. Tymoczko, Gregory J. Gatto, and Lubert Stryer. Biochemistry . 8th ed. W. H. Freeman & Co., 2015. ISBN: 9781464126109.
    Listed reading
  • [MM] = Miesfeld, Roger L., and Megan M. McEvoy. Biochemistry . W. W. Norton & Company, 2017. ISBN: 9780393614022.
    Listed reading
  • Readings are from Berg, Tymockzko, Gatto, and Stryer Biochemistry (8th edition) OR from Miesfeld & McEvoy Biochemistry . Read one or the other. There is no need to read both.
    Listed reading
  • Berg, Jeremy M., John L. Tymoczko, Gregory J. Gatto, and Lubert Stryer. Biochemistry . 8th ed. W. H. Freeman & Co., 2015. ISBN: 9781464126109.
    Listed reading
  • Miesfeld, Roger L., and Megan M. McEvoy. Biochemistry . W. W. Norton & Company, 2017. ISBN: 9780393614022.
    Listed reading
  • Stryer is the traditional textbook in this course, and is one of the classic textbooks in the field of biochemistry (the other two being Lehninger, and Vogt and Vogt). Many of your professors learned biochemistry from one or more of these three books.
    Listed reading
  • Miesfeld and McEvoy is an alternative textbook that presents the material in a slightly different style than Stryer. It contains more recent material, and may be a bit more fun to read.
    Listed reading

Prerequisites & course information

Prereq: ( Biology (GIR) and 5.12 ) or permission of instructor U (Spring) 5-0-7 units. REST Credit cannot also be received for 5.07[J] , 20.507[J]

Sources