Principles of Biochemical Analysis

6-0-6 units · Graduate

Principles of protein biochemistry, emphasizing structure, equilibrium studies, kinetics, and experimental design. Topics include macromolecular binding and specificity, allosteric systems, mechanisms of inhibition, enzyme principles, single-molecule studies, structure-function relationships, molecular evolution, and library methods. Case studies examine mechanisms of transcription factors, kinases, molecular machines, and other proteins.