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7.60

Cell Biology: Structure and Functions of the Nucleus

3-0-9 units · Graduate

Eukaryotic genome structure, function, and expression in normal cells and how this becomes dysregulated in disease. Emphasis on the techniques and logic used to address important problems in nuclear cell biology. Lectures on broad topic areas in nuclear cell biology and discussions on representative recent papers.

Spring 2010

The goal of this course is to teach both the fundamentals of nuclear cell biology as well as the methodological and experimental approaches upon which they are based. Lectures and class discussions will cover the background and fundamental findings in a particular area of nuclear cell biology. The assigned readings will provide concrete examples of the experimental approaches and logic used to establish these findings. Some examples of topics include genome and systems biology, transcription, and gene expression.

Readings

Prerequisites & course information

Prereq: 7.06 or permission of instructor G (Spring) 3-0-9 units

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