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7.88

Protein Folding in Health and Disease

3-0-3 units · Graduate

See description under subject 5.48[J] .

Spring 2015 · Protein Folding and Human Disease

Topics

  • Introduction to Class
  • Protein Conformation Review
  • β-sheet Conformations
  • Critical Features of in Vitro Refolding Reactions
  • Structure and Function of Double Barrel Chaperonins
  • Collagen Folding and Assembly
  • Protein Deposition Diseases: Light Chain Amyloidosis, Alzheimers, Parkinson’s, Huntington’s, ALS and Others
  • Prions and Functional Amyloids
  • Membrane Proteins
  • Chaperones
  • Student Paper Presentations

Prerequisites & course information

Same subject as 5.48[J] Prereq: ( 5.07[J] or 7.05 ) and permission of instructor G (Spring; first half of term) 3-0-3 units

Sources