Topics in Computational and Systems Biology
See description under subject CSB.100[J] . Preference to first-year CSB PhD students.
Fall 2010
This is a seminar based on research literature. Papers covered are selected to illustrate important problems and approaches in the field of computational and systems biology, and provide students a framework from which to evaluate new developments. The MIT Initiative in Computational and Systems Biology ({{% resource_link "2348453e-d4c8-4530-ab42-438ec0082b73" "CSBi" %}}) is a campus-wide research and education program that links biology, engineering, and computer science in a multidisciplinary approach to the systematic analysis and modeling of complex biological phenomena. This course is one of a series of core subjects offered through the CSB Ph.D. program, for students with an interest in interdisciplinary training and research in the area of computational and systems biology.
Readings
- Benjamini, Eli, Richard Coico, and Geoffrey Sunshine. Chapters 1, 7, and 17 in Immunology: A Short Course . 5th ed. Hoboken, NJ: Wiley, 2003. ISBN: 9780471226895.
- (The first chapter gives a basic overview of immunology; chapter 7, p. 91 talks about B lymphocytes; and chapter 17, pp. 249-255, talks about lymphomas.)
- Zvelebil, Marketa, and Jeremy O. Baum. Understanding Bioinformatics . New York, NY: Garland Science, 2007. ISBN: 9780815340249. (Note: this text is highly recommended for 7.91 also)
- Alon, Uri. An Introduction to Systems Biology: Design Principles of Biological Circuits . Boca Raton, FL: Chapman & Hall, 2006. ISBN: 9781584886426. (A newer book that’s worth a look — systems biology from a physicist’s perspective.)
- Watson, J. D., T. A. Baker, S. P. Bell, A. Gann, M. Levine, and R. Losick. Molecular Biology of the Gene . 6th ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 2007. ISBN: 9780805395921. (An updated version of the classic text.)
- Alberts, B., A. Johnson, J. Lewis, M. Raff, K. Roberts, and P. Walter. Molecular Biology of the Cell . 5th ed. New York, NY: Garland Science, 2008. ISBN: 9780815341055. (Another classic text.)
- Berg, J. M., J. L. Tymoczko, and L. Stryer. Biochemistry . 6th ed. New York, NY: W.H. Freeman, 2007. ISBN: 9780716787242. (Yet another classic.)
- Branden, C., and J. Tooze. Introduction to Protein Structure . 2nd ed. New York, NY: Garland Pub., 1999. ISBN: 9780815323051. (A gentle but authoritative introduction to the topic.)
Prerequisites & course information
Same subject as CSB.100[J] Prereq: Permission of instructor G (Fall) 2-0-10 units
Sources
- Course catalogue ↗2026–2027
- MIT OpenCourseWare ↗Fall 2010
- MIT OCW readings ↗
- MIT OCW syllabus ↗
- Historical MIT OpenCourseWare offering. Named reading entries and schedule topics are automatically extracted from the linked source pages.