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HST.121

Gastroenterology

3-1-2 units · Graduate

Presents the anatomy, physiology, biochemistry, biophysics, and bioengineering of the gastrointestinal tract and associated pancreatic, liver, and biliary systems. Emphasis on the molecular and pathophysiological basis of disease where known. Covers gross and microscopic pathology and clinical aspects. Formal lectures given by core faculty, with some guest lectures by local experts. Selected seminars conducted by students with supervision of faculty. Only HST students may register under HST.120, graded P/D/F. Enrollment limited.

Fall 2005

The most recent knowledge of the anatomy, physiology, biochemistry, biophysics, and bioengineering of the gastrointestinal tract and the associated pancreatic, liver and biliary tract systems is presented and discussed. Gross and microscopic pathology and the clinical aspects of important gastroenterological diseases are then presented, with emphasis on integrating the molecular, cellular and pathophysiological aspects of the disease processes to their related symptoms and signs.

Readings

  • Cotran, Ramzi S., Vinay Kumar, Tucker Collins, and Stanley L. Robbins. “The Gastrointestinal Tract,” “Liver and the Biliary Tract,” and “The Pancreas.” Chapters 18, 19, and 20 in Robbins Pathological Basis of Diseases . 6th ed. Philadelphia, PA: W.B. Saunders Co., 1999. ISBN: 9780721673356 .
    Recommended
  • Heuman, Douglas M., A. Scott Mills, and Hunter H. McGuire. Gastroenterology , Saunders Text and Review Series . Philadelphia, PA: W.B. Saunders Co., 1997. ISBN: 9780721658643.
    Recommended
  • Chandrasoma, P. Gastrointestinal Pathology . Stamford, CT: Appleton & Lange, 1999. ISBN: 9780838530931.
    Listed reading
  • Fawcett, D. W., W. Bloom, et al. A Textbook of Histology . New York, NY: Chapman & Hall, 1997. ISBN: 9780412046919 .
    Listed reading
  • Fenoglio-Preiser, C. M. Gastrointestinal Pathology: An Atlas and Text . Philadelphia, PA: Lippincott-Raven Publishers, 1999. ISBN: 9780397516407.
    Listed reading
  • Ming, S.-C., and H. Goldman. Pathology of the Gastrointestinal Tract . Baltimore, MD: Williams & Wilkins, 1998. ISBN: 9780683180077.
    Listed reading
  • MacSween, R. N. M. Pathology of the Liver . Edinburgh, Scotland; New York, NY: Churchill Livingstone, 2002. ISBN: 9780443061813.
    Listed reading
  • Gore, R. M., and M. S. Levine. Textbook of Gastrointestinal Radiography . Philadelphia, PA: W.B. Saunders Co., 2000. ISBN: 9780721678368.
    Listed reading
  • Schiff, E. R., M. F. Sorrell, et al. Schiff’s Diseases of the Liver . Philadelphia, PA: Lippincott-Raven Publishers, 1999. ISBN: 9780781719445.
    Listed reading
  • Sherlock, S., and J. Dooley. Diseases of the Liver and Biliary System . Oxford, UK; Malden, MA: Blackwell Science, 2002. ISBN: 9780632055821.
    Listed reading
  • Feldman, M., B. Scharschmidt, et al. Sleisenger and Fordtran’s Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management . 7th ed. Philadelphia, PA: W.B. Saunders Co., 2002. ISBN: 9780721689739.
    Listed reading
  • Tahara, E. Molecular Pathology of Gastroenterological Cancer: Application to Clinical Practice . Tokyo, Japan; New York, NY: Springer, 1997. ISBN: 9784431701958.
    Listed reading
  • Zakim, D., and Boyer T. Hepatology: A Textbook of Liver Disease. 4th ed. Philadelphia, PA: W.B. Saunders Co., 2002. ISBN: 9997618912.
    Listed reading

Prerequisites & course information

Subject meets with HST.120 Prereq: Biology (GIR) , Physics I (GIR) , 7.05 , and permission of instructor G (Fall; second half of term) 3-1-2 units

Sources