Tumor Microenvironment and Immuno-Oncology: A Systems Biology Approach
Provides theoretical background to analyze and synthesize the most up-to-date findings from both laboratory and clinical investigations into solid tumor pathophysiology. Covers different topics centered on the critical role that the tumor microenvironment plays in the growth, invasion, metastasis and treatment of solid tumors. Develops a systems-level, quantitative understanding of angiogenesis, extracellular matrix, metastatic process, delivery of drugs and immune cells, and response to conventional and novel therapies, including immunotherapies. Discussions provide critical comments on the challenges and the future opportunities in research on cancer and in establishment of novel therapeutic approaches and biomarkers to guide treatment.
Fall 2005 · Tumor Pathophysiology and Transport Phenomena
Tumor pathophysiology plays a central role in the growth, invasion, metastasis and treatment of solid tumors. This class applies principles of transport phenomena to develop a systems-level, quantitative understanding of angiogenesis, blood flow and microcirculation, metabolism and microenvironment, transport and binding of small and large molecules, movement of cancer and immune cells, metastatic process, and treatment response. **Additional Faculty** Dr. Pat D'Amore Dr. Dan Duda Dr. Robert Langer Prof. Robert Weinberg Dr. Marsha Moses Dr. Raghu Kalluri Dr. Lance Munn
Prerequisites & course information
Same subject as 10.548[J] Prereq: None Acad Year 2027-2028: Not offered Acad Year 2028-2029: G (Fall) 2-0-4 units
Sources
- Course catalogue ↗2026–2027
- MIT OpenCourseWare ↗Fall 2005
- MIT OCW syllabus ↗
- Historical MIT OpenCourseWare offering. Named reading entries and schedule topics are automatically extracted from the linked source pages.