HST.560
Radiation Biophysics
See description under subject 22.55[J] .
Fall 2004 · Principles of Radiation Interactions
Topics
- Course Intro/Cells and Tissues Overview
- Radiation Interactions
- Radiation Interactions (cont.)
- Radiation Chemistry/LET/Tracks
- Effects on Chromosomes/DNA
- Dose Response in Vitro: Cell Survival Curves
- RBE/Clustered Damage
- Protons and Alphas of same LET
- Dose Response in Vivo
- Chemical Modification of Radiation Response
- Cell, Tissue and Tumor Kinetics
- Radiation Therapy: Tumor Radiobiology
- Radiation Therapy (contd.): Fractionation
- Acute Effects of Whole Body Exposure
- Late Effects: Chronic Exposure/Low Doses
- Radiation Protection/Background Radiation/Radon
- Alpha Particles/Bystander Effect
- Microbeams
- RBE of Diagnostic X Rays
- BNCT/Other Modalities
- Space
- Space (cont.)
- Oral Term Paper Presentations
Readings
- Rydberg, Björn, William R. Holley, I. Saira Mian, and Aloke Chatterjee. “Chromatin Conformation in Living Cells: Support for a Zig-Zag Model of the 30 nm Chromatin Fiber.” Journal of Molecular Biology 284 (1998): 71-84.
- Holley, W. R., I. S. Mian, S. J. Park, B. Rydberg, and A. Chatterjee. “A Model for Interphase Chromosomes and Evaluation of Radiation-Induced Aberrations.” Radiation Research 158 (2002): 568–580.
- Dikomey, E., J. Dahm-Daphi, I. Brammer, R. Martensen, and B. Kaina. “Correlation between Cellular Radiosensitivity and Non-repaired Double-strand Breaks Studied in Nine Mammalian Cell Lines.” International Journal of Radiation Biology 73, no. 3 (1998): 269-278.
- Löbrich, M., P. K. Cooper, and B. Rydberg. “Non-random Distribution of DNA Double-strand Breaks Induced by Particle Irradiation.” International Journal of Radiation Biology 70, no. 5 (1996): 493-503.
- The chapters in the table below are from: Hall, Eric J. Radiobiology for the Radiologist . 5th ed. Philadelphia: Lippincott Williams & Wilkins, 2000. ISBN: 9780781726498.
- SES #: 2 · TOPICS: Radiation Interactions · READINGS: Chapter 1
- SES #: 4 · TOPICS: Radiation Chemistry/LET/Tracks · READINGS: Chapter 7
- SES #: 5 · TOPICS: Effects on Chromosomes/DNA · READINGS: Chapter 2
- SES #: 6 · TOPICS: Dose Response in Vitro: Cell Survival Curves · READINGS: Chapter 3
- SES #: 9 · TOPICS: Dose Response in Vivo · READINGS: Chapters 18 and 20
- SES #: 10 · TOPICS: Chemical Modification of Radiation Response · READINGS: Chapters 6, 9 and 25
- SES #: 11 · TOPICS: Cell, Tissue and Tumor Kinetics · READINGS: Chapters 4 and 5
- SES #: 13 · TOPICS: Radiation Therapy: Tumor Radiobiology · READINGS: Chapter 21
- SES #: 14 · TOPICS: Radiation Therapy (contd.): Fractionation · READINGS: Chapter 19
- SES #: 15 · TOPICS: Acute Effects of Whole Body Exposure · READINGS: Chapter 8
- SES #: 16 · TOPICS: Late Effects: Chronic Exposure/Low Doses · READINGS: Chapters 10, 11 and 12
- SES #: 17 · TOPICS: Radiation Protection/Background Radiation/Radon · READINGS: Chapter 15
- SES #: 21 · TOPICS: BNCT/Other Modalities · READINGS: Chapters 24, 27 and 28
- Hall, Eric J. Radiobiology for the Radiologist . 5th ed. Philadelphia: Lippincott Williams & Wilkins, 2000. ISBN: 0781726429.
- Turner, J. E. Atoms, Radiation, and Radiation Protection. 2nd ed. New York: J. Wiley, 1995. ISBN: 9780471595816.
- Tubiana, M., J. Dutreix, and A. Wambersie. Introduction to Radiobiology. London, New York, Philadelphia: Taylor and Francis, 1990. ISBN: 9780850667455.
- Alpen, Edward L. Radiation Biophysics . 2nd ed. San Diego: Academic Press, 1998. ISBN: 9780120530854.
- Lodish, Berk, Zipursky, Matsudaira, Baltimore, and Darnell. Molecular Cell Biology. 4th ed. New York: W.H. Freeman and Company, 2003. ISBN: 9780716743668.
Prerequisites & course information
Same subject as 22.55[J] Subject meets with 22.055 Prereq: Permission of instructor Acad Year 2027-2028: G (Fall) Acad Year 2028-2029: Not offered 3-0-9 units
Sources
- Course catalogue ↗2026–2027
- MIT OpenCourseWare ↗Fall 2004
- MIT OCW readings ↗
- MIT OCW syllabus ↗
- MIT OCW calendar ↗
- Historical MIT OpenCourseWare offering. Named reading entries and schedule topics are automatically extracted from the linked source pages.