Nervous System Development

(3 Credit Hours) · Undergraduate

This module forms part of the core curriculum for the BSc degree in Neuroscience. The course introduces the development of the nervous system at a molecular, cellular and systems level along with core underlying principles. We outline the anatomical growth and division of the brain and its driving forces such as gene expression, developmental signalling and cell population expansion, and consider questions such as neural induction, polarity/segmentation, differentiation, cell migration, axon growth/guidance, target selection, synapse formation/maturation and neuronal maintenance. Also, general properties of inter- and intra- cellular signaling and communication relevant to neurons will be outlined. The course also contains a number of practicals, where students will be introduced to brain anatomy as well as a 2-day animal development practial where students will follow the development of frog embryos from fertilisation to neurulation.